# Vertex Pharmaceuticals operating income entity: /record/vertex-pharmaceuticals.md predicate: operating_income page: /record/vertex-pharmaceuticals/operating_income as_of: 2026-11-10 cite: AsOf. "Vertex Pharmaceuticals quarterly operating income: 712,900,000 United States dollar", as of 2026-09-30. Claim clm_60BA65E99F72, https://asof.is/claim/clm_60BA65E99F72, accessed 2026-11-10. Source: https://www.sec.gov/Archives/edgar/data/875320/000087532026000291/0000875320-26-000291-index.htm. As of November 10, 2026, the latest operating income figure on the AsOf record for Vertex Pharmaceuticals is $712.9 million for the quarter ended September 30, 2026, from a primary source (sec.gov). Vertex Pharmaceuticals's latest full-year operating income is $4.17 billion, dated December 31, 2025, from a primary source (sec.gov); the two periods are kept apart, never compared. 18 claims on Vertex Pharmaceuticals's operating income, 1 open and 17 superseded, each dated and sourced; a replaced value is closed with an end date, never deleted. ## Latest operating income The newest figure for a shorter period, the quarter ended September 30, 2026: a quarterly_operating_income claim, kept apart from the full-year series. - [Vertex Pharmaceuticals](/record/vertex-pharmaceuticals.md) | quarterly_operating_income | 712,900,000 United States dollar | valid 2026-09-30 to present | conf 0.95 | valid | [clm_60BA65E99F72](/claim/clm_60BA65E99F72.md) sources: https://www.sec.gov/Archives/edgar/data/875320/000087532026000291/0000875320-26-000291-index.htm ## Latest full-year operating income What the record asserts on 2026-11-10. - [Vertex Pharmaceuticals](/record/vertex-pharmaceuticals.md) | operating_income | 4,173,300,000 United States dollar | valid 2025-12-31 to present | conf 0.95 | valid | [clm_08B6F6FEE28A](/claim/clm_08B6F6FEE28A.md) sources: https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/0000875320-26-000056-index.htm ## Every dated value One claim per line, oldest first. Superseded claims stay visible. - [Vertex Pharmaceuticals](/record/vertex-pharmaceuticals.md) | operating_income | -462,708,000 United States dollar | valid 2008-12-31 to 2009-12-31 | conf 0.95 | superseded | superseded_by [clm_9AF280BB8EE3](/claim/clm_9AF280BB8EE3.md) | [clm_FEC47F071AB0](/claim/clm_FEC47F071AB0.md) sources: https://www.sec.gov/Archives/edgar/data/875320/000104746911001025/0001047469-11-001025-index.htm - [Vertex Pharmaceuticals](/record/vertex-pharmaceuticals.md) | operating_income | -614,012,000 United States dollar | valid 2009-12-31 to 2010-12-31 | conf 0.95 | superseded | superseded_by [clm_9472043EC2FF](/claim/clm_9472043EC2FF.md) | [clm_9AF280BB8EE3](/claim/clm_9AF280BB8EE3.md) sources: https://www.sec.gov/Archives/edgar/data/875320/000104746911001025/0001047469-11-001025-index.htm - [Vertex Pharmaceuticals](/record/vertex-pharmaceuticals.md) | operating_income | -696,077,000 United States dollar | valid 2010-12-31 to 2011-12-31 | conf 0.95 | superseded | superseded_by [clm_E814D4173C5E](/claim/clm_E814D4173C5E.md) | [clm_9472043EC2FF](/claim/clm_9472043EC2FF.md) sources: https://www.sec.gov/Archives/edgar/data/875320/000104746911001025/0001047469-11-001025-index.htm - [Vertex Pharmaceuticals](/record/vertex-pharmaceuticals.md) | operating_income | 113,820,000 United States dollar | valid 2011-12-31 to 2012-12-31 | conf 0.95 | superseded | superseded_by [clm_4F9C4EE9CB90](/claim/clm_4F9C4EE9CB90.md) | [clm_E814D4173C5E](/claim/clm_E814D4173C5E.md) sources: https://www.sec.gov/Archives/edgar/data/875320/000104746912001298/0001047469-12-001298-index.htm - [Vertex Pharmaceuticals](/record/vertex-pharmaceuticals.md) | operating_income | 2,332,000 United States dollar | valid 2012-12-31 to 2013-12-31 | conf 0.95 | superseded | superseded_by [clm_A3A048BBF066](/claim/clm_A3A048BBF066.md) | [clm_4F9C4EE9CB90](/claim/clm_4F9C4EE9CB90.md) sources: https://www.sec.gov/Archives/edgar/data/875320/000087532013000009/0000875320-13-000009-index.htm - [Vertex Pharmaceuticals](/record/vertex-pharmaceuticals.md) | operating_income | -903,448,000 United States dollar | valid 2013-12-31 to 2014-12-31 | conf 0.95 | superseded | superseded_by [clm_729B31AEC767](/claim/clm_729B31AEC767.md) | [clm_A3A048BBF066](/claim/clm_A3A048BBF066.md) sources: https://www.sec.gov/Archives/edgar/data/875320/000087532014000015/0000875320-14-000015-index.htm - [Vertex Pharmaceuticals](/record/vertex-pharmaceuticals.md) | operating_income | -692,412,000 United States dollar | valid 2014-12-31 to 2015-12-31 | conf 0.95 | superseded | superseded_by [clm_B6F6CDFC9E0A](/claim/clm_B6F6CDFC9E0A.md) | [clm_729B31AEC767](/claim/clm_729B31AEC767.md) sources: https://www.sec.gov/Archives/edgar/data/875320/000087532015000012/0000875320-15-000012-index.htm - [Vertex Pharmaceuticals](/record/vertex-pharmaceuticals.md) | operating_income | -466,879,000 United States dollar | valid 2015-12-31 to 2016-12-31 | conf 0.95 | superseded | superseded_by [clm_C74861030CDE](/claim/clm_C74861030CDE.md) | [clm_B6F6CDFC9E0A](/claim/clm_B6F6CDFC9E0A.md) sources: https://www.sec.gov/Archives/edgar/data/875320/000087532016000067/0000875320-16-000067-index.htm - [Vertex Pharmaceuticals](/record/vertex-pharmaceuticals.md) | operating_income | 9,936,000 United States dollar | valid 2016-12-31 to 2017-12-31 | conf 0.95 | superseded | superseded_by [clm_03E98C0A4208](/claim/clm_03E98C0A4208.md) | [clm_C74861030CDE](/claim/clm_C74861030CDE.md) sources: https://www.sec.gov/Archives/edgar/data/875320/000087532017000017/0000875320-17-000017-index.htm - [Vertex Pharmaceuticals](/record/vertex-pharmaceuticals.md) | operating_income | 123,243,000 United States dollar | valid 2017-12-31 to 2018-12-31 | conf 0.95 | superseded | superseded_by [clm_30D3676BC4AE](/claim/clm_30D3676BC4AE.md) | [clm_03E98C0A4208](/claim/clm_03E98C0A4208.md) sources: https://www.sec.gov/Archives/edgar/data/875320/000087532018000009/0000875320-18-000009-index.htm - [Vertex Pharmaceuticals](/record/vertex-pharmaceuticals.md) | operating_income | 635,150,000 United States dollar | valid 2018-12-31 to 2019-12-31 | conf 0.95 | superseded | superseded_by [clm_05A793B89218](/claim/clm_05A793B89218.md) | [clm_30D3676BC4AE](/claim/clm_30D3676BC4AE.md) sources: https://www.sec.gov/Archives/edgar/data/875320/000087532019000006/0000875320-19-000006-index.htm - [Vertex Pharmaceuticals](/record/vertex-pharmaceuticals.md) | operating_income | 1,197,566,000 United States dollar | valid 2019-12-31 to 2020-12-31 | conf 0.95 | superseded | superseded_by [clm_227207794AE5](/claim/clm_227207794AE5.md) | [clm_05A793B89218](/claim/clm_05A793B89218.md) sources: https://www.sec.gov/Archives/edgar/data/875320/000087532020000007/0000875320-20-000007-index.htm - [Vertex Pharmaceuticals](/record/vertex-pharmaceuticals.md) | operating_income | 2,856,290,000 United States dollar | valid 2020-12-31 to 2021-12-31 | conf 0.95 | superseded | superseded_by [clm_DB3896AB26E8](/claim/clm_DB3896AB26E8.md) | [clm_227207794AE5](/claim/clm_227207794AE5.md) sources: https://www.sec.gov/Archives/edgar/data/875320/000087532021000006/0000875320-21-000006-index.htm - [Vertex Pharmaceuticals](/record/vertex-pharmaceuticals.md) | operating_income | 2,782,100,000 United States dollar | valid 2021-12-31 to 2022-12-31 | conf 0.95 | superseded | superseded_by [clm_EA4DD24E67F5](/claim/clm_EA4DD24E67F5.md) | [clm_DB3896AB26E8](/claim/clm_DB3896AB26E8.md) sources: https://www.sec.gov/Archives/edgar/data/875320/000087532022000007/0000875320-22-000007-index.htm - [Vertex Pharmaceuticals](/record/vertex-pharmaceuticals.md) | operating_income | 4,307,400,000 United States dollar | valid 2022-12-31 to 2023-12-31 | conf 0.95 | superseded | superseded_by [clm_EDF03CE5BDB7](/claim/clm_EDF03CE5BDB7.md) | [clm_EA4DD24E67F5](/claim/clm_EA4DD24E67F5.md) sources: https://www.sec.gov/Archives/edgar/data/875320/000087532023000007/0000875320-23-000007-index.htm - [Vertex Pharmaceuticals](/record/vertex-pharmaceuticals.md) | operating_income | 3,832,000,000 United States dollar | valid 2023-12-31 to 2024-12-31 | conf 0.95 | superseded | superseded_by [clm_33A4466539E6](/claim/clm_33A4466539E6.md) | [clm_EDF03CE5BDB7](/claim/clm_EDF03CE5BDB7.md) sources: https://www.sec.gov/Archives/edgar/data/875320/000087532024000062/0000875320-24-000062-index.htm - [Vertex Pharmaceuticals](/record/vertex-pharmaceuticals.md) | operating_income | -232,900,000 United States dollar | valid 2024-12-31 to 2025-12-31 | conf 0.95 | superseded | superseded_by [clm_08B6F6FEE28A](/claim/clm_08B6F6FEE28A.md) | [clm_33A4466539E6](/claim/clm_33A4466539E6.md) sources: https://www.sec.gov/Archives/edgar/data/875320/000087532025000053/0000875320-25-000053-index.htm - [Vertex Pharmaceuticals](/record/vertex-pharmaceuticals.md) | operating_income | 4,173,300,000 United States dollar | valid 2025-12-31 to present | conf 0.95 | valid | [clm_08B6F6FEE28A](/claim/clm_08B6F6FEE28A.md) sources: https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/0000875320-26-000056-index.htm ## What replaced what - -$462.71 million (2008-12-31 to 2009-12-31, [clm_FEC47F071AB0](/claim/clm_FEC47F071AB0.md)) was replaced by -$614.01 million from 2009-12-31 ([clm_9AF280BB8EE3](/claim/clm_9AF280BB8EE3.md)) - -$614.01 million (2009-12-31 to 2010-12-31, [clm_9AF280BB8EE3](/claim/clm_9AF280BB8EE3.md)) was replaced by -$696.08 million from 2010-12-31 ([clm_9472043EC2FF](/claim/clm_9472043EC2FF.md)) - -$696.08 million (2010-12-31 to 2011-12-31, [clm_9472043EC2FF](/claim/clm_9472043EC2FF.md)) was replaced by $113.82 million from 2011-12-31 ([clm_E814D4173C5E](/claim/clm_E814D4173C5E.md)) - $113.82 million (2011-12-31 to 2012-12-31, [clm_E814D4173C5E](/claim/clm_E814D4173C5E.md)) was replaced by $2.33 million from 2012-12-31 ([clm_4F9C4EE9CB90](/claim/clm_4F9C4EE9CB90.md)) - $2.33 million (2012-12-31 to 2013-12-31, [clm_4F9C4EE9CB90](/claim/clm_4F9C4EE9CB90.md)) was replaced by -$903.45 million from 2013-12-31 ([clm_A3A048BBF066](/claim/clm_A3A048BBF066.md)) - -$903.45 million (2013-12-31 to 2014-12-31, [clm_A3A048BBF066](/claim/clm_A3A048BBF066.md)) was replaced by -$692.41 million from 2014-12-31 ([clm_729B31AEC767](/claim/clm_729B31AEC767.md)) - -$692.41 million (2014-12-31 to 2015-12-31, [clm_729B31AEC767](/claim/clm_729B31AEC767.md)) was replaced by -$466.88 million from 2015-12-31 ([clm_B6F6CDFC9E0A](/claim/clm_B6F6CDFC9E0A.md)) - -$466.88 million (2015-12-31 to 2016-12-31, [clm_B6F6CDFC9E0A](/claim/clm_B6F6CDFC9E0A.md)) was replaced by $9.94 million from 2016-12-31 ([clm_C74861030CDE](/claim/clm_C74861030CDE.md)) - $9.94 million (2016-12-31 to 2017-12-31, [clm_C74861030CDE](/claim/clm_C74861030CDE.md)) was replaced by $123.24 million from 2017-12-31 ([clm_03E98C0A4208](/claim/clm_03E98C0A4208.md)) - $123.24 million (2017-12-31 to 2018-12-31, [clm_03E98C0A4208](/claim/clm_03E98C0A4208.md)) was replaced by $635.15 million from 2018-12-31 ([clm_30D3676BC4AE](/claim/clm_30D3676BC4AE.md)) - $635.15 million (2018-12-31 to 2019-12-31, [clm_30D3676BC4AE](/claim/clm_30D3676BC4AE.md)) was replaced by $1.2 billion from 2019-12-31 ([clm_05A793B89218](/claim/clm_05A793B89218.md)) - $1.2 billion (2019-12-31 to 2020-12-31, [clm_05A793B89218](/claim/clm_05A793B89218.md)) was replaced by $2.86 billion from 2020-12-31 ([clm_227207794AE5](/claim/clm_227207794AE5.md)) - $2.86 billion (2020-12-31 to 2021-12-31, [clm_227207794AE5](/claim/clm_227207794AE5.md)) was replaced by $2.78 billion from 2021-12-31 ([clm_DB3896AB26E8](/claim/clm_DB3896AB26E8.md)) - $2.78 billion (2021-12-31 to 2022-12-31, [clm_DB3896AB26E8](/claim/clm_DB3896AB26E8.md)) was replaced by $4.31 billion from 2022-12-31 ([clm_EA4DD24E67F5](/claim/clm_EA4DD24E67F5.md)) - $4.31 billion (2022-12-31 to 2023-12-31, [clm_EA4DD24E67F5](/claim/clm_EA4DD24E67F5.md)) was replaced by $3.83 billion from 2023-12-31 ([clm_EDF03CE5BDB7](/claim/clm_EDF03CE5BDB7.md)) - $3.83 billion (2023-12-31 to 2024-12-31, [clm_EDF03CE5BDB7](/claim/clm_EDF03CE5BDB7.md)) was replaced by -$232.9 million from 2024-12-31 ([clm_33A4466539E6](/claim/clm_33A4466539E6.md)) - -$232.9 million (2024-12-31 to 2025-12-31, [clm_33A4466539E6](/claim/clm_33A4466539E6.md)) was replaced by $4.17 billion from 2025-12-31 ([clm_08B6F6FEE28A](/claim/clm_08B6F6FEE28A.md)) ## Questions this record answers ### What is Vertex Pharmaceuticals's current operating income? The latest figure on the record is $712.9 million for the quarter ended September 30, 2026, from a primary source (sec.gov). The latest full-year figure is $4.17 billion, dated December 31, 2025, from a primary source (sec.gov). The record asserts both as of November 10, 2026. ### What was Vertex Pharmaceuticals's operating income for the quarter ended September 30, 2026? $712.9 million for the quarter ended September 30, 2026, dated September 30, 2026, from a primary source (sec.gov) (status valid, confidence 0.95). ### When did Vertex Pharmaceuticals's operating income last change? The latest value on the record is $4.17 billion, dated December 31, 2025; before it the record holds -$232.9 million, dated December 31, 2024 and closed on December 31, 2025. ### What was Vertex Pharmaceuticals's operating income before $4.17 billion? -$232.9 million, valid from December 31, 2024 to December 31, 2025 (status superseded), from a primary source (sec.gov). ## Read on - This page: /record/vertex-pharmaceuticals/operating_income (markdown: /record/vertex-pharmaceuticals/operating_income.md) - Entity twin: /record/vertex-pharmaceuticals.md ยท timeline: /timelines/vertex-pharmaceuticals.md --- AsOf is a temporal fact ledger: a structured, dated, sourced record of what is true and what changed, built for AI retrieval.